Set the UpdateMode to Conditional to create a nested update panel , so that the parent update panel will not get refreshed when the child is being refreshed.

<pre lang=”vb.net”>

<form id=”form1″ runat=”server”>

<asp:ScriptManager ID=”ScriptManager1″ runat=”server”>

</asp:ScriptManager>

<div>

<table width=”80%” border=”3″>

<tr>

<td>

Label outside all the Update Panels

<asp:Label ID=”Label3″ runat=”Server” Font-Bold=”true”></asp:Label>

<br />

<br />

<asp:Button ID=”Button3″ runat=”Server” Text=”Refresh” />

<br />

<br />

</td>

</tr>

<tr>

<td>

<table width=”65%” border=”2″>

<tr>

<td>

<asp:UpdatePanel ID=”UpdatePanel1″ runat=”server” UpdateMode=”Conditional”>

<ContentTemplate>

Label within the Parent Update Panel

<asp:Label ID=”Label1″ runat=”server” Font-Bold=”true”></asp:Label>

<br />

<br />

<asp:Button ID=”Button1″ runat=”server” Text=”Refresh” />

<table width=”40%” border=”1″>

<tr>

<td>

<asp:UpdatePanel ID=”UpdatePanel2″ runat=”server” UpdateMode=”Conditional”>

<ContentTemplate>

<br />

<br />

Label within the Child Update Panel

<asp:Label ID=”Label2″ runat=”server” Font-Bold=”True”></asp:Label>

<br />

<br />

<asp:Button ID=”Button2″ runat=”server” Text=”Refresh” />

</ContentTemplate>

</asp:UpdatePanel>

</td>

</tr>

</table>

</ContentTemplate>

</asp:UpdatePanel>

</td>

</tr>

</table>

</td>

</tr>

</table>

</div>

</form>

Code behind

protected void Page_Load(object sender, EventArgs e)

{

Label1.Text = System.DateTime.Now.ToString();

Label2.Text = System.DateTime.Now.ToString();

Label3.Text = System.DateTime.Now.ToString();

}

</pre>

<a href=”http://geekswithblogs.net/ranganh/archive/2007/05/16/112525.aspx”>Source</a>